Alanine Aminotransferase



Alanine aminotransferase (ALT) measurements are useful in the diagnosis and treatment of certain liver diseases (e.g., viral hepatitis and cirrhosis) and heart disease. ALT is an enzyme involved in amino acid metabolism and is, therefore, found in many tissues. The highest levels of ALT are found in the liver and kidney tissues. Tissue destruction leads to the release of the intracellular enzyme into the circulating blood. Markedly elevated serum ALT levels may be found in a variety of diseases which involve the liver, such as hepatitis, mononucleosis and cirrhosis. These very high levels of ALT are not usually observed in other diseases processes, e.g. myocardial infarction, thus ALT is regarded as a reasonably specific indicator of liver disease.

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Alanine Aminotransferase


Serum Separator Tube (SST®)

Do not remove the stopper at any time. Do not centrifuge immediately after drawing blood. Allow the blood to clot in an upright position for at least 30 minutes but not longer than 1 hour before centrifugation. Centrifuge for at least 15 minutes at 2200-2500 RPM within one hour of collection. Label the tube with the patient’s last name, patient’s first name, date of birth, date of collection, and time of collection.

Room temperature:
Refrigerated: 72 hours