Magnesium is an essential factor in many important enzymatic reactions, either as an integral part of a metalloenzyme or as an activator, and plays an important role in glycolysis, cellular respiration and transmembranous calcium transport. Magnesium is mainly regulated by the rate of renal magnesium excretion, which along with calcium is subject to the effects of parathyroid hormone. Increasing calcium reabsorption thus leads to competitive inhibition of magnesium absorption. Magnesium measurements are used in the diagnosis and treatment of hypomagnesemia (abnormally low) and hypermagnesemia (abnormally high). The best-defined manifestation of magnesium deficiency is impairment of neuromuscular function e.g. hyperirritability, tetany, convulsions, and electrocardiographic changes. Hypomagnesemia is observed in cases of diabetes, chronic alcoholism, forced diuresis, hyperthyroidism, hypoparathyroidism, hypocalcemia, malabsorption and acute pancreatitis. Increased serum magnesium levels have been found in cases of renal failure, dehydration, severe diabetic acidosis and Addison’s Disease.

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Serum Separator Tube (SST®)

Do not remove the stopper at any time. Do not centrifuge immediately after drawing blood. Allow the blood to clot in an upright position for at least 30 minutes but not longer than 1 hour before centrifugation. Centrifuge for at least 15 minutes at 2200-2500 RPM within one hour of collection. Label the tube with the patient’s last name, patient’s first name, date of birth, date of collection, and time of collection.

Room temperature:
Refrigerated: 7 Days