Shiga-like toxin-producin



Shiga-like toxin-producing E. coli (STEC), including E. coli O157. There are two main types of Shiga-like toxins, Shiga-like toxin 1 (Stx1) and Shiga-like toxin 2 (Stx2) (also known as verotoxins). Shiga-like toxin-producing E. coli (STEC) may contain either one or both stx genes. STEC are a primary cause of bloody diarrhea10,36 and can progress to a potentially fatal condition known as hemolytic uremic syndrome (HUS; caused by Shiga-like toxin destruction of red blood cells that leads to renal failure), especially in the very young and very old. STEC are important foodborne pathogens. Infections may also be waterborne, transmitted person-to-person, or via contact with animals (especially cattle, which are a reservoir for STEC). Antimicrobial therapy for STEC may lead to an increased risk for HUS, especially in antibioticresistant strains, potentially by up-regulating production and thus increasing the amount of Shiga-like toxin available for absorption. Therefore, identification of Shiga-like toxin genes in a patient with gastrointestinal illness can aid in the decision of whether or not to prescribe antibiotics for patient care.

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Shiga-like toxin-producin
Cary Blair

Stool specimens should be collected in Cary Blair transport media according to manufacturer’s instructions.

Room temperature: 4 hours
Refrigerated: 3 days
Frozen: Not acceptable


1 – 24 hours from recept at lab