Adenovirus F 40/41. Adenoviruses are double-stranded DNA viruses of the Adenoviridae family that cause a variety of diseases including respiratory illness and gastrointestinal illness. They are resistant to chemical and physical damage and are thus persistent in the environment, facilitating transmission. There are seven species of Adenoviruses (A-G) that are further categorized into approximately 57 serotypes, however GI illness is primarily associated with species F (which is comprised of serotypes 40 and 41). Adenovirus F 40/41 is responsible for 5 to 15% of all acute diarrheal illness in children (especially in those under two years of age).10 Transmission is mostly through fecal-oral spread and outbreaks have been reported in hospitals and child care centers. While Adenovirus infections mostly occur in children, adults may be affected as well.10 Illness is generally mild but of a relatively long duration (5-12 days). Immunocompromised patients may suffer chronic, prolonged diarrheal illness and other complications. Virus may be shed in stool for weeks to months following acute illness; therefore identification of infected individuals may be important for patient isolation and control of disease spread.
1 – 24 hours from recept at lab